Volume 8, Issue 3, September 2014, Pages 1296–1312
Nurul Huda1, Mohd Rashid2, and Harun Rashid3
1 Malaysia-Japan International Institute of Technology, 54100 UTM Kuala Lumpur, Malaysia
2 Malaysia Japan International Institute of Technology, Department of Environment & Green Technology, UTM, Kuala Lumpur, Malaysia
3 International University of Business Agriculture & Technology, Department of Chemistry, Dhaka, Malaysia
Original language: English
Copyright © 2014 ISSR Journals. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
In the past few years, an increasing number of stimuli responsive thin polymer films and intelligent hydrogels have been reported in the literature for various biomedical applications, including drug delivery, tissue engineering and wound healing. The thermo-sensitive approach can be advantageous for some specific applications as it does not require organic solvents, co-polymerization agents, or an externally applied trigger for gelation. The conformation as well as change in physical properties of polymer brushes and polymer hydrogel can be influenced by the environmental stimuli, such as solvent composition, temperature, pH and electric fields. This review focuses on the recent advances of these stimuli responsive molecular thin film and stimuli responsive polymeric gels with unique properties and utilities. We also discuss some conflicting behaviors shown by polymer grafted membrane and polymer gel surfaces, synthesized by using same monomers. Major properties of stimuli responsive thin polymer films, and on their potential application in the field of nano-optics, ultrasensitive spectroscopies and other biomedical applications including drug delivery are also outlined.
Author Keywords: drug delivery system, molecularly imprinted polymer, nanoparticles, stimuli-responsive.
Nurul Huda1, Mohd Rashid2, and Harun Rashid3
1 Malaysia-Japan International Institute of Technology, 54100 UTM Kuala Lumpur, Malaysia
2 Malaysia Japan International Institute of Technology, Department of Environment & Green Technology, UTM, Kuala Lumpur, Malaysia
3 International University of Business Agriculture & Technology, Department of Chemistry, Dhaka, Malaysia
Original language: English
Copyright © 2014 ISSR Journals. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
In the past few years, an increasing number of stimuli responsive thin polymer films and intelligent hydrogels have been reported in the literature for various biomedical applications, including drug delivery, tissue engineering and wound healing. The thermo-sensitive approach can be advantageous for some specific applications as it does not require organic solvents, co-polymerization agents, or an externally applied trigger for gelation. The conformation as well as change in physical properties of polymer brushes and polymer hydrogel can be influenced by the environmental stimuli, such as solvent composition, temperature, pH and electric fields. This review focuses on the recent advances of these stimuli responsive molecular thin film and stimuli responsive polymeric gels with unique properties and utilities. We also discuss some conflicting behaviors shown by polymer grafted membrane and polymer gel surfaces, synthesized by using same monomers. Major properties of stimuli responsive thin polymer films, and on their potential application in the field of nano-optics, ultrasensitive spectroscopies and other biomedical applications including drug delivery are also outlined.
Author Keywords: drug delivery system, molecularly imprinted polymer, nanoparticles, stimuli-responsive.
How to Cite this Article
Nurul Huda, Mohd Rashid, and Harun Rashid, “A Review on Stimuli-responsive grafted membranes Based on Facile Synthesis Process and Extensive Applications,” International Journal of Innovation and Applied Studies, vol. 8, no. 3, pp. 1296–1312, September 2014.
