Volume 16, Issue 1, May 2016, Pages 19–24
Fouad AKIF1 and Franck Genten2
1 Centre Régional des Métiers d’Education et de Formation (CRMEF) Souss Massa Darea, Morocco
2 Laboratoire de Biopathologie Vétérinaire, Faculté de Médecine, Université Libre de Bruxelles, Belgium
Original language: English
Copyright © 2016 ISSR Journals. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
We investigated histochemically the expression of glycans in the mouse ventral prostate of the normal, castrated, castrated mice injected with testosterone (T) and castrated mice injected with dihydrotestosterone (DHT). The avidin-biotin-peroxidase complex technique was used with eight biotinylated lectins, on paraffin sections. Remarkably, contrarily to T, the DHT found to restore all the glycans in epithelial cells of ventral prostate. The histophysiological significance of the activation synthesis of glycoconjugates in mouse ventral prostate by DHT is discussed in the light of the other studies obtained mainly in humans.
Author Keywords: Ventral prostate, lectins, Testosterone, Dihydrotestosterone, Glycohistochemistry.
Fouad AKIF1 and Franck Genten2
1 Centre Régional des Métiers d’Education et de Formation (CRMEF) Souss Massa Darea, Morocco
2 Laboratoire de Biopathologie Vétérinaire, Faculté de Médecine, Université Libre de Bruxelles, Belgium
Original language: English
Copyright © 2016 ISSR Journals. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
We investigated histochemically the expression of glycans in the mouse ventral prostate of the normal, castrated, castrated mice injected with testosterone (T) and castrated mice injected with dihydrotestosterone (DHT). The avidin-biotin-peroxidase complex technique was used with eight biotinylated lectins, on paraffin sections. Remarkably, contrarily to T, the DHT found to restore all the glycans in epithelial cells of ventral prostate. The histophysiological significance of the activation synthesis of glycoconjugates in mouse ventral prostate by DHT is discussed in the light of the other studies obtained mainly in humans.
Author Keywords: Ventral prostate, lectins, Testosterone, Dihydrotestosterone, Glycohistochemistry.
How to Cite this Article
Fouad AKIF and Franck Genten, “Restoration of the glycoconjugates expression in the ventral prostate of androgen-deprived mice by dihydrotestosterone: A glycohistochemical study,” International Journal of Innovation and Applied Studies, vol. 16, no. 1, pp. 19–24, May 2016.
