International Journal of Innovation and Applied Studies
ISSN: 2028-9324     CODEN: IJIABO     OCLC Number: 828807274     ZDB-ID: 2703985-7
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Whooping Cough

[ La Coqueluche ]

Volume 18, Issue 2, October 2016, Pages 416–424

 Whooping Cough

Meryem ELGARINI1, Abderrahmane Hammoumi2, Zakaria Mennane3, Aicha Qasmaoui4, and Reda Charof5

1 Laboratoire de Microbiologie, Pharmacologie, Biotechnologie et Environnement, Faculté des sciences Ain Chock, Université Hassan II Casablanca, Morocco
2 Laboratoire de Microbiologie, Pharmacologie, Biotechnologie et Environnement, Faculté des sciences Ain Chock, Université Hassan II Casablanca, Morocco
3 Department of Medical Bacteriology, National Institute of Hygiene, Ibn Battuta Avenue, B.P. 769, Agdal, Rabat 11000, Morocco
4 Département Bactériologie Médicale, Institut National d’Hygiène Rabat, Morocco
5 Department of medical bacteriology, National Institute of hygiene, Rabat, Morocco

Original language: French

Copyright © 2016 ISSR Journals. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Pertussis or whooping cough is a highly contagious infection of the respiratory tract caused by the bacterium albordtella pertussis. It’s a disease that could affects human at all his stages of life and the infection may be repeated several times, but gravity is reflected in babies given the complications that can lead to death. Over the last decades, the disease have increased although vaccines. And because of the decreased immunity against this disease among adults and adolescents, making them vulnerable, they become a source of infection for children who have not yet received the vaccine or have not completed the initial vaccination.

Author Keywords: Bordetella pertussis, Firulence factors, Toxin of pertussis, Morocco, epidemiology.

Abstract: (french)

La coqueluche est une infection respiratoire, bactérienne, strictement humaine, due à Bordetella pertussis, coccobacille à Gram négatif qui sécrètent toxines et adhésines, sont responsables des effets cytopathogènes locaux et systémiques observés lors de la maladie tels la destruction de l’épithélium respiratoire cilié et l’hyperlymphocytose. Elle touche l'homme à tout âge. On peut avoir la maladie plusieurs fois au cours de la vie. La vaccination des enfants a permis la diminution de la morbidité et de la mortalité par la coqueluche, mais l’épidémiologie s’est transformée sous l’effet de la vaccination. La coqueluche est désormais fréquente chez l’adolescent et l’adulte mais méconnue, ce qui contribue à la pérennisation de la circulation de Bordetella pertussis et à la contamination de jeunes nourrissons qui font les formes les plus sévères. Ces bactéries extracellulaires, En raison de ce danger pour les nourrissons, plusieurs pays,,ont ajouté des rappels vaccinaux pour l’adolescent et l’adulte.

Author Keywords: Bordetella pertussis, Facteurs de virulence, Toxine de pertussis, Maroc, Epidémiologie.

How to Cite this Article

Meryem ELGARINI, Abderrahmane Hammoumi, Zakaria Mennane, Aicha Qasmaoui, and Reda Charof, “Whooping Cough,” International Journal of Innovation and Applied Studies, vol. 18, no. 2, pp. 416–424, October 2016.