The aim of this study was to develop an ointment of cosmetic interest in order to offer populations a hair product with local ingredients, a study of formulation and conditioning of the ointment was undertaken using oils of Elæis guineensis as active and of Butyrospermum. parkii as an excipient. These two species are known in communities for their use in hair maintenance and growth. The formulation consisted of a mixture of these two oils in precise proportions to obtain a single homogeneous phase. The ointment obtained coded PKP was applied to male and female rabbits of the species Oryctolagus cuniculus previously shaved at the rate of two applications per day for 28 days. Hair growth was measured each two days. In addition, sterility, stability and skin tolerability were assessed. The PKP ointment obtained was moderately hard, homogeneous, with a very pleasant odor and a pH of 3.93. After 28 days of experimentation, the results showed that hair growth in male rabbits was greater with a maximum cumulative length of 21 mm. The ointment did not show any microbial contamination and it remained stable over time. PKP is an ointment that would stimulate hair growth and would be a very good alternative to fight against early hair loss.

We studied the cutaneous MISCA-MATES toxicity soap humans. The test of irritation at the man is indispensable to specify the potential irritating power of some better cosmetic preparations. Thirty soaps of MISCA-MATÈS experimentation were delayed on thirty voluntary people. Two methods have been used. The first consists in applying a quantity of soap foam on the hand of the volunteers during 24 hours. The test has been repeated at the same place during 7 days except if an erythema develops in which case the test is stopped. The treatment has not been interrupted after the 7 days of experimentation. The second method consists in distributing to each volunteer a soap for the bath during 7 days and we noted the effects which could produce the soap on their respective skins. The analysis shows that one person out of thirty (3.33 %) felt a slight burn when applying soap while twenty nine persons (96.67 %) felt no burn.

Chloroquine has been widely used in the treatment of uncomplicated Plasmodium falciparum malaria. Unfortunately, because of chemoresistance emergence and its spread worldwide since the 1960's, substitute medicines were compulsory to fight against malaria efficiently.
Therefore, current priority of the fight against malaria is to search for substances capable to improve back chloroquine efficacy.
The present work highlights life threatening action of Olax subscorpio

To evaluate the in vitro chemosensitivity to Atovaquone (ATQ) and analyze polymorphism of Pfcytb gene of Plasmodium falciparum isolates from Abidjan. Fifty seven isolates of P. falciparum collected between 2010 and 2012 from the outskirts of the city of Abidjan. Were used for testing in vitro susceptibility according to the microtest optical version of the World Health Organization (WHO). Polymerase Chain Reaction (PCR) was used to determine mutation in the Pfcytb gene. The analysis of the relationship between the observed mutations and chemosensitivity of isolates was made using Cohen's kappa test. The geometric mean IC50 of atovaquone is 1,645 mM. All 57 isolates were sensitive to atovaquone. The 29 isolates of P. falciparum sequenced showed no mutation of Pcytb gene at codon Y268. No other mutation was observed. Our study showed no correlation between phenotypic and molecular data (K< 0). This study shows that the combination atovaquone / proguanil can be one of the drugs of choice for the prophylaxis of multidrug-resistant falciparum malaria recommended by the World Health Organization (WHO).