Introduction: High Blood Pressure (HBP) is an important cause of morbidity through the world. It repeals to an arterial systolic pressure of more or equal to 140 mmHg and a diastolic pressure of more or equal to 90 mm Hg. The aim of this study was to determinate the epidemiological aspects of High Blood Pressure in patients at Matanda hospital. Method: This was a descriptive cross-sectional survey, covering the period from January 1st 2017 to December 31st 2018. It concerned 4464 inpatients admitted in Internal Medicine department at Matanda Hospital. Were included in this survey all patients hospitalized in internal medicine service, and whose medical files have been found and fully completed. Result: The frequency of the HBP is 5.29%. The following parameters have been found as risk factors of HBP: the age group of 61 years old and above, male sex, the married people, the widows, Housekeepers, People who practice God ministry, the state agents, tabaco use, alcoholism and diabetes mellitus. Headaches, vertigo and the amaurosis were the most found subjective signs, whereas epis²²tasis, loss of awareness and palpitation were the most seen objective signs in HBP patients. The checkup for cholesterol and ECG were the most realized investigations and Captopril is the mostly used drug. Deaths due to HBP have represented 11.44%. Conclusion: The prevention of HBP, a silent killer, should be more highlighted during the management of patient with HBP as this disease constitutes a heavy economic and social burden.