The objective of this work was to evaluate the improvement indices and the agro-morphological diversity of Ceratotheca sesamoides accessions from the Sudan-Sahelian and Sudanian climatic zones of Burkina Faso. For this purpose, a randomized Fisher block design with three replications was set up. Univariate analysis was used to evaluate the level of diversity and the varietal improvement indices. The evaluation of the links between the traits was done by Person’s correlation test. The structuring of the diversity was done by multivariate analyses. The results of this experiment reveal the existence of a high agro-morphological diversity on several traits. This diversity made it possible to divide the accessions collected into four groups. Of these, group I is made up of the best performing accessions. The best performing traits were dry and fresh leaf biomass, plant height and number of primary branches. The genetic parameters recorded that Group I accessions are best suited in a breeding and development program for the creation of varieties that meet the needs of producers. The study assessed the level of diversity, diversity structuring and improvement indices.