Traditional henna rarely causes adverse events. However, to obtain a black color, many ingredients are mixed with this plant such as paraphenylene diamine and solvents. The aim of our study is to describe severe cutaneous adverse events caused by black henna collected at the Moroccan Pharmacovigilance Centre. Materials and Methods: We analyzed the coetaneous adverse reactions associated with the use of black henna, collected during 2012 in Morocco. The severity ofreactions wasan inclusion criteria. We analyzed the characteristics of patients, adverse reactions and type of exposure. Results: Nine serious cutaneous cases were collected, which represent 6.42% of all adverse reactions related to cosmetics products. Hospitalization and sequelae were the reason of seriousness. Outcomes were favorable for all cases. Conclusion: the severity of those cases showed the importance of the pharmacovigilance of cosmetics products.