Streptococcus agalactiae or group B streptococcus (GBS) is a common agent of maternal and neonatal infections. Invasives diseases due to GBS are increasing in non-pregnant adults, mainly for immunodepressed adults with a mortality rate ranging from 20% to 50%.Among these infections, meningitis streptococcus agalactiae are exceptional. This observation reports the case of meningitis Streptococcus agalactiae in a diabetic patient. The urinary tract was the starting point of the invasive infection due to GBS.