This work aims to evaluate the antimalarial biological activities of medicinal plant extracts namely Artemisia annua, Alisicarpus ovalifolius and Securidaka longepediculata. The phytochemical analysis of the extracts of these plants revealed the presence of saponins, alkaloids, flavonoids, quinones, phenols and terpenes. Toxicity tests according to the method proposed by OECD have made it possible to conclude that the plant extracts are not toxic. The tests were carried out on mice, inoculated intraperitoneally with Plasmodium berghei. These animals were divided into eleven groups of five, nine of which each received a dose of the extract to be tested and the other two, distilled water for the negative control and arthemether for the positive control. The different extracts showed various antimalarial activities using the four-day Peters test on infected mice. Artemisia annua gave the highest parasitaemia reduction percentages with 87.2; 96.8 and 96% respectively at doses of 100, 250 and 500 mg/kg, while Alisicarpus ovalifolius recorded 61.6; 71.20 and 80.8% respectively at the same doses. Securidaka longepediculata extracts gave low percentage reductions in parasitaemia. Statistical analysis reveals that the extracts showed a significant difference compared to the negative control (P<0.05).

In Burkina Faso, Water resources are threatened today by pollution from domestic waste, industrial and agricultural discharges without adequate treatment. This pollution is the main cause of degradation of water quality. The objective of this study is to evaluate the physicochemical quality of the water in the market garden site of Kossodo watered with sewage sludge from the city of Ouagadougou industries. Indeed, seven (7) wastewater samples collected over a 90 days period at the site where a Water Treatment Plant (WTP) was installed were analysed in the laboratory. The parameters were pH, EC, Ca2+, Mg2+, Na+, K+, Cl-, SO42-, NH4+, NO3-, HCO3-, CO32- , BOD5, SM and COD. The analytical data was compared to WHO standards. The Results show that the concentrations of the chemical elements are very high in the wastewater, but hardly exceed the levels recommended by the standards for agro-pastoral needs. Electrical conductivity indicates that 57% of the samples analysed are not saline. Phosphorus and potassium concentrations are low. There is a strong mineralization resulting from industrial or domestic pollution. The physicochemical characterization of the raw wastewater revealed that this liquid discharge is very heavy in organic matter in term of COD (Avg.= 341.52 mg/L), in BDO5 (Avg.= 260 mg/L), in Suspend Matter (Avg.= 307.6 mg/L) and mineral matter expressed in terms of chlorides (Avg.= 75.968 mg/L), electric conductivity (Avg.= 580.24 µs/cm) and alkalinity expressed as CaCO3 (Avg.= 220.70 mg/L) with a pH of 7.5 (±0.3). The average levels of nitrates and orthophosphates respectively of the order of 33.11 mg/L and 86.74 mg/L. Over the entire sampled site, most of the wastewater analysed is suitable for agriculture.