[ Forme virilisante de tumeur juvénile de la granulosa de l'ovaire: A propos d'un cas ]
Volume 15, Issue 1, March 2016, Pages 14–23
Ayman Hachi1, Majdouline Boujoual2, Adil Chennana3, Rachid Frikh4, Abdellah Babahabib5, Moulay Elmehdi Elhassani6, Jaouad Kouach7, Driss Rahali Moussaoui8, and Mohammed Dehayni9
1 Service de Gynécologie Obstétrique, Hôpital Militaire d'Instruction Mohammed V Rabat, Morocco
2 Gynécologie Obstétrique, Hôpital Militaire d’Instruction Mohammed V (HMIMV), Faculté de Médecine et de Pharmacie de Tanger, Université Abdelmalek Essaadi, Morocco
3 Service de Gynécologie Obstétrique, Hôpital Militaire d'Instruction Mohammed V Rabat, Morocco
4 Service de dermatologie, Hôpital Militaire d'Instruction Mohammed V Rabat, Morocco
5 Department of obstetrics & gynecology, Military Training Hospital Mohamed V, Rabat, Morocco
6 Gynécologie - Obstétrique, Hôpital Militaire Instructif Mohamed V, Rabat, Morocco
7 Faculté de Médecine et de Pharmacie, Université Mohamed V, Rabat, Morocco
8 Department of Gynecology-Obstetric, Military Training Hospital Med V, Rabat, Morocco
9 Department of Gynecology-Obstetric, Military Training Hospital Med V, Faculty of Medicine and Pharmacy, Mohammed V University, Rabat, Morocco
Original language: French
Copyright © 2016 ISSR Journals. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Juvenile granulosa tumor is a sex cord stromal tumor extremely rare, with usually estrogenic effects, while virilizing form is exceptional, often discovered at a stage confined to the ovary, justifying therefore a conservative treatment. Its prognosis appears favorable, depending on early management. However, its evolvement may be hampered by early and aggressive recurrence.
We report a new case compiled in Obstetrics Gynecology Service (HMIMV) of virilizing form of juvenile granulosa cell tumors, discovered during a recent exacerbation of a preexisting androgen syndrome in a girl of 24 years. It's extreme rarity prompted us to report it highlighting, through a literature review, its diagnostic features, therapeutic and evolutionary.
Author Keywords: Granulosa cell tumor, juvenile form, virilizing.
Volume 15, Issue 1, March 2016, Pages 14–23
Ayman Hachi1, Majdouline Boujoual2, Adil Chennana3, Rachid Frikh4, Abdellah Babahabib5, Moulay Elmehdi Elhassani6, Jaouad Kouach7, Driss Rahali Moussaoui8, and Mohammed Dehayni9
1 Service de Gynécologie Obstétrique, Hôpital Militaire d'Instruction Mohammed V Rabat, Morocco
2 Gynécologie Obstétrique, Hôpital Militaire d’Instruction Mohammed V (HMIMV), Faculté de Médecine et de Pharmacie de Tanger, Université Abdelmalek Essaadi, Morocco
3 Service de Gynécologie Obstétrique, Hôpital Militaire d'Instruction Mohammed V Rabat, Morocco
4 Service de dermatologie, Hôpital Militaire d'Instruction Mohammed V Rabat, Morocco
5 Department of obstetrics & gynecology, Military Training Hospital Mohamed V, Rabat, Morocco
6 Gynécologie - Obstétrique, Hôpital Militaire Instructif Mohamed V, Rabat, Morocco
7 Faculté de Médecine et de Pharmacie, Université Mohamed V, Rabat, Morocco
8 Department of Gynecology-Obstetric, Military Training Hospital Med V, Rabat, Morocco
9 Department of Gynecology-Obstetric, Military Training Hospital Med V, Faculty of Medicine and Pharmacy, Mohammed V University, Rabat, Morocco
Original language: French
Copyright © 2016 ISSR Journals. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Juvenile granulosa tumor is a sex cord stromal tumor extremely rare, with usually estrogenic effects, while virilizing form is exceptional, often discovered at a stage confined to the ovary, justifying therefore a conservative treatment. Its prognosis appears favorable, depending on early management. However, its evolvement may be hampered by early and aggressive recurrence.
We report a new case compiled in Obstetrics Gynecology Service (HMIMV) of virilizing form of juvenile granulosa cell tumors, discovered during a recent exacerbation of a preexisting androgen syndrome in a girl of 24 years. It's extreme rarity prompted us to report it highlighting, through a literature review, its diagnostic features, therapeutic and evolutionary.
Author Keywords: Granulosa cell tumor, juvenile form, virilizing.
Abstract: (french)
La tumeur juvénile de la granulosa est une tumeur stromale des cordons sexuels extrêmement rare, ayant habituellement des effets oestrogéniques, alors que sa forme virilisante est exceptionnelle. Elle est souvent découverte à un stade confiné à l'ovaire, justifiant alors un traitement conservateur. Son pronostic semble favorable, dépend de la précocité de la prise en charge. Toutefois, son évolution peut être grevée par des récidives précoces et plus agressives.
Nous rapportons un nouveau cas colligé au service de Gynécologie Obstétrique (HMIMV) d'une forme virilisante des tumeurs juvéniles de la granulosa, découverte à l'occasion d'une exacerbation récente d'un syndrome androgénique préexistant chez une jeune fille de 24ans. Son extrême rareté nous a incités à le rapporter en insistant, à travers une revue de littérature, sur ses caractéristiques diagnostiques, thérapeutiques et évolutives.
Author Keywords: tumeurs des cellules de la granulosa, forme juvénile, virilisante.
How to Cite this Article
Ayman Hachi, Majdouline Boujoual, Adil Chennana, Rachid Frikh, Abdellah Babahabib, Moulay Elmehdi Elhassani, Jaouad Kouach, Driss Rahali Moussaoui, and Mohammed Dehayni, “Virilizing form of ovarian juvenile granulosa tumor: A case report,” International Journal of Innovation and Applied Studies, vol. 15, no. 1, pp. 14–23, March 2016.
