Volume 35, Issue 2, January 2022, Pages 425–435
Loukou N’Goran Etienne1, N’Goran K. Edouard2, Yao Kouadio René Patrice3, Yassongui Mamadou Sekongo4, Koua Ago Bénédicte5, Zede Elisée6, and Yapi-Gnaore Chia Valentine7
1 Unité de Formation et de Recherche en Sciences Biologiques, Biochimie-Génétique, Université Peleforo Gon-Coulibaly, Korhogo, Côte d’Ivoire
2 Unité de Formation et de Recherche en Sciences Biologiques, Biochimie-Génétique, Université Peleforo Gon-Coulibaly, Korhogo, Côte d’Ivoire
3 Centre National de Transfusion Sanguine, Centre Hospitalier Régionale, Korhogo, Côte d’Ivoire
4 Centre National de Transfusion Sanguine, Centre Hospitalier Régionale, Korhogo, Côte d’Ivoire
5 Unité de Formation et de Recherche en Sciences Biologiques, Biochimie-Génétique, Université Peleforo Gon-Coulibaly, Korhogo, Côte d’Ivoire
6 Centre National de Transfusion Sanguine, Centre Hospitalier Régionale, Korhogo, Côte d’Ivoire
7 Centre International de Recherche-Développement sur l'Elevage en zone Subhumide (CIRDES), Bobo Dioulasso, Burkina Faso
Original language: English
Copyright © 2022 ISSR Journals. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
A study was carried out on 632 consenting donors at the National Blood Transfusion Centre (CNTS) of the Regional Hospital of Korhogo Northern in Côte d'Ivoire to contribute to a better supply of human blood to health facilities through knowledge of the genetic frequencies of the ABO and Rhesus systems. Individual donor interviews were used to collect socio-cultural data, and the Beth-Vincent blood test and the Simonin serum test were used to perform manual blood grouping. The research showed that there are more men (92.25 %) than women (7.57 %), with approximately 1 woman for every 12 men. The average age of the donors was 33 years. The Gour ethnic group was the most common (61.06 %), followed by the Mandé (26.36 %). The phenotypic frequencies [O], [B], [A], and [AB] of the ABO system were observed in proportions of 46.52 %, 28.80 %, 19.62 %, and 5.06 %, respectively. The Rh (D) factor was 92.72 % for [Rh (D) +] and 07.28 % for [Rh (D) -] respectively. Sociological factors had no effect on the distribution of blood groups. The O allele is the most common (0.682) in this population, followed by the B and A alleles, which have frequencies of 0.186 and 0.132, respectively. The Rh (D) + allele predominated, with a frequency of 0.74 compared to 0.26 for the Rh (d) allele. According to the Hardy-Weinberg law, these various genetic structures are in panmictic equilibrium.
Author Keywords: ABO/Rh systems, genetic frequencies, blood donors, Korhogo.
Loukou N’Goran Etienne1, N’Goran K. Edouard2, Yao Kouadio René Patrice3, Yassongui Mamadou Sekongo4, Koua Ago Bénédicte5, Zede Elisée6, and Yapi-Gnaore Chia Valentine7
1 Unité de Formation et de Recherche en Sciences Biologiques, Biochimie-Génétique, Université Peleforo Gon-Coulibaly, Korhogo, Côte d’Ivoire
2 Unité de Formation et de Recherche en Sciences Biologiques, Biochimie-Génétique, Université Peleforo Gon-Coulibaly, Korhogo, Côte d’Ivoire
3 Centre National de Transfusion Sanguine, Centre Hospitalier Régionale, Korhogo, Côte d’Ivoire
4 Centre National de Transfusion Sanguine, Centre Hospitalier Régionale, Korhogo, Côte d’Ivoire
5 Unité de Formation et de Recherche en Sciences Biologiques, Biochimie-Génétique, Université Peleforo Gon-Coulibaly, Korhogo, Côte d’Ivoire
6 Centre National de Transfusion Sanguine, Centre Hospitalier Régionale, Korhogo, Côte d’Ivoire
7 Centre International de Recherche-Développement sur l'Elevage en zone Subhumide (CIRDES), Bobo Dioulasso, Burkina Faso
Original language: English
Copyright © 2022 ISSR Journals. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
A study was carried out on 632 consenting donors at the National Blood Transfusion Centre (CNTS) of the Regional Hospital of Korhogo Northern in Côte d'Ivoire to contribute to a better supply of human blood to health facilities through knowledge of the genetic frequencies of the ABO and Rhesus systems. Individual donor interviews were used to collect socio-cultural data, and the Beth-Vincent blood test and the Simonin serum test were used to perform manual blood grouping. The research showed that there are more men (92.25 %) than women (7.57 %), with approximately 1 woman for every 12 men. The average age of the donors was 33 years. The Gour ethnic group was the most common (61.06 %), followed by the Mandé (26.36 %). The phenotypic frequencies [O], [B], [A], and [AB] of the ABO system were observed in proportions of 46.52 %, 28.80 %, 19.62 %, and 5.06 %, respectively. The Rh (D) factor was 92.72 % for [Rh (D) +] and 07.28 % for [Rh (D) -] respectively. Sociological factors had no effect on the distribution of blood groups. The O allele is the most common (0.682) in this population, followed by the B and A alleles, which have frequencies of 0.186 and 0.132, respectively. The Rh (D) + allele predominated, with a frequency of 0.74 compared to 0.26 for the Rh (d) allele. According to the Hardy-Weinberg law, these various genetic structures are in panmictic equilibrium.
Author Keywords: ABO/Rh systems, genetic frequencies, blood donors, Korhogo.
How to Cite this Article
Loukou N’Goran Etienne, N’Goran K. Edouard, Yao Kouadio René Patrice, Yassongui Mamadou Sekongo, Koua Ago Bénédicte, Zede Elisée, and Yapi-Gnaore Chia Valentine, “POLYMORPHISM OF BLOOD SYSTEMS ABO AND RH (D) IN A BLOOD DONORS POPULATION OF THE KORHOGO NATIONAL BLOOD TRANSFUSION CENTRE,” International Journal of Innovation and Applied Studies, vol. 35, no. 2, pp. 425–435, January 2022.
