The use of synthetic pesticides may present a danger to humans and the environment, to the point that the research of an alternative to these chemicals is necessary. The present study, aimed finding new natural molecules that may replace synthetic chemicals, looked at the effect of the ethanolic extract of B.grandiflora bark on eight seed-borne phytopathogenic fungi. The results of this study showed that C. lunata and C. dematium are the most sensitive to the ethanolic extract. This attests the presence of fungicidal or fungistatic substances in B. grandiflora bark. These results show that the ethanolic extract contains active molecules which, once fractionated, could constitute an alternative in the fight against phytopathogenic fungi. These preliminary results open up the possibility of using the bark of B. grandiflora for the production of a natural fungicide. Bioguided fractionation and phytotoxicity tests will identify the most active and non-toxic fractions which could be use in seed protection.