The main objective of this thesis is to show the contribution of human capital on economic growth in Cameroon. To do this, we specified a multi-equation model on time series data spanning over a period of 36 years (1980 - 2015). We have formulated a system of three simultaneous equations that we had analysed by DMC (Doubles Least Square) and GMM methods due to our Eviews (7.1) software. Conceptual work shows that an educated and healthy population is generally more productive. The results are quite diverse. Literacy shows a negatively and significantly result at a point of 5%, while health shows a positive and non-significant result. The GDP per head remains ambiguous and contradictory when going from one equation to another. Conclusively, the impact of social factors (literacy and health) is condition by political, economic and social stability.