The objective of the study was to evaluate the influence of Tithonia diversifolia in association with three hilling moments in order to identify the best moment (s) associated with Tithonia diversifolia improve soil fertility and thus give bean plants the ability to withstand the attack of bean flies and thus hope to have good yield of common beans. The experimental design was the split plot with three repetitions, with beans’ variety called Kirundo as the main plots. They were subdivided into two subplots, one of which corresponded to the application of Tithonia diversifolia and the other without Tithonia diversifolia. The main plots were nine in total and constituted six different treatments evaluated. A single fresh biomass dose of Tithonia diversifolia equivalent to 10 tons per hectare was applied in all plots with Tithonia d. two weeks before sowing beans. There were significant differences between treatments. Bean’ yield increased by an average of 212.28%, the weight of 100 seeds was improved by an average of 7.2%, the number of pupae such as the cumulative number of dead bean plants was significantly reduced by application of Tithonia diversifolia in this highly endemic study environment for bean maggot, the vigor of bean plants has been improved, there has been no interaction between Tithonia diversifolia and ridging at any given time. In conclusion, the application of Tithonia diversifolia increased bean yield in soil with many soil fertility constraints and highly endemic for bean maggot (Ophiomya spp).