Onion bulbs production and commercialization is now a powerful tool against poverty in rural areas in Burkina Faso. However, Fusarium basal rot disease caused by a complex of soilborne fungi appears to be a serious threat to growers. The prophylactic methods proposed for its control remain difficult to apply effectively and the most used varieties of onion are susceptible to the disease. In order to work out a palliative solution to this problem, eleven onion varieties marketed in Burkina Faso were screened for their tolerance to fusarium basal rot. The varieties were produced in infested rural area on completely randomized blocs by three producers in three different sites. The harvested bulbs were then tested in the laboratory under artificial inoculation conditions with conidial suspensions of Fusarium oxysporum and F. solani, responsible for the disease. In field, the Noflaye and Gandiol+ varieties were the most tolerant to the disease with respective incidence values ​​of 0 and 1.6% while the Mercedes variety was the most sensitive with an incidence of 16,5%. In the laboratory, all the inoculated varieties developed rot at varying intensities, but the Noflaye and Gandiol+ varieties were still the least rotten. These results recommend the continuation of investigations on these two varieties with a view to their integration into an integrated control program against Fusarium basal rot disease of onion in Burkina Faso.