The objective of this study was to evaluate, in a semi-controlled environment, the resistance of twelve (12) new rice genotypes (KBR2, KBR4, KBR6, KBR8, KBR9, KBR11, KBR12, KBR13, KBR15, KBR17, KBR28, KBR42) to rice blast caused by Magnaporthe oryzae in Burkina Faso. The experimental design used was a randomised block with three (03) replications. The parameters assessed were leaf and panicle severity, leaf and panicle incidence, yield per pot and percentage yield loss. The results showed that genotypes KBR11, KBR15 and KBR42 were resistant to medium resistance to blast, with values ranging from 7.7% to 15% of leaf area diseased and from 14% to 24.07% of panicles diseased. These genotypes recorded the best yields per pot of 60.32g/pot, 65.97g/pot and 60.43g/pot respectively, with relatively low yield losses. Genotypes KBR11, KBR15 and KBR42 were resistant to medium resistance to leaf and panicle blast with high yield performance and relatively low yield loss rates. These genotypes can be used to control rice blast in rice fields in Burkina Faso. They therefore need to be improved and made more widely available. This will require the support of agricultural research, extension services and farm advisory services.