Objective: Identify differential elements of magnetic resonance imaging (MRI), functional and metabolic to differentiate brain lymphomas and malignant gliomas, since both high grade tumor entities may show similar appearance on structural MR imaging.
Materials and methods: The MRI sequences diffusion, perfusion and spectroscopy of 22 patients with 6 primary central nervous system lymphoma and 16 holders of malignant gliomas, were analyzed retrospectively.
Results: We found that the apparent diffusion coefficient (ADC) lymphoma lesions is less than or equal to that of healthy tissue contralateral. The perfusion lymphomas, has a relative cerebral blood volume (rCBV), slightly increased, on average between 1 and 2 times normal and a characteristic curve with a passage above the baseline. No increased perfusion zone, strictly greater than the contralateral healthy parenchyma was recorded in lymphomas, whereas malignant glioma tumor areas have always frankly hyperperfus
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