The cutaneous leishmaniasis (CL) is a vector of parasitic disease which is transmitted via a dipterous insect bite, the phlebotomus. It always poses a problem for public health in Morocco and in many countries. It is a widespread pathology that develops under sporadic or endemic form. Having for objective to analyse the epidemiological situation of cutaneous leishmaniasis within Meknes prefecture and to detect the locations that are at risk to transmit this disease. We have offered to conduct a retrospective study of the cutaneous leishmaniasis cases registered at the level of this prefecture all along the period of 2009 through 2013. This research aims to analyse the annual segmentation of the cutaneous leishmaniasis cases according to urban or rural locations as well as the level of incidence by commune and by sectors. Data used is adopted for the epidemiological surveillance inserted in the register of the Epidemiological cell of the prefecture. The studied variables are: the number of cases, the year, the place, and the sector. To collect and to analyse data, we have used excel application. A total of 56 cases are registered by the prefectural cell of epidemiology (EPC) all along the period of 2009 through 2013 among which 56 percent are from the rural areas. 46 percent are from the urban locations. We have equally observed that this pathology spreads in the majority of sectors and locations in the prefecture, with a variable scale of incidence depending on the years. A predominance of the rural sectors :( DKHISSA and Wallili) is noted. In addition, to some urban sectors: (Sidi Amer, Ras Aghil) to take the case 2012 incidence: in respect to the following data : 65.1 ;59.1;23.64; 9.49. These findings are worth reconsideration by other studies in order to determine the ecology and dynamics of the population vector of this disease within range of the main locations of this prefecture.