[ Carcinome métaplasique du sein : A propos de deux cas ]
Volume 23, Issue 3, June 2018, Pages 285–289
Aida Abida1, Dalal Kacimi2, Mounia El Youssfi3, and Samir Bargach4
1 Service de gynécologie obstétrique cancérologie et grossesse à haut risque, Maternité Souissi, Université Mohamed V, Rabat, Morocco
2 Service de gynécologie obstétrique cancérologie et grossesse à haut risque, maternité Souissi, Université Mohamed V, Morocco
3 Service de gynécologie obstétrique cancérologie et grossesse à haut risque, maternité Souissi, Université Mohamed V, Rabat, Morocco
4 Department of Gynecology-Obstetrics-Oncology and High-Risk Pregnancy, Souissi Maternity Hospital, Ibn Sina University Hospital Center, Rabat, Morocco
Original language: French
Copyright © 2018 ISSR Journals. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Metaplastic breast carcinomas are rare tumors, represent less than 1% of invasive breast cancers, and constitute a heterogeneous group of tumors defined by the World Health Organization as infiltrating ductal carcinoma but with zones of metaplastic rearrangements of Epidermoid, fusiform, chondroid, bone or mixed type. Histopathology combined with immunohistochemistry makes it possible to make the diagnosis. Treatment combines surgery, and chemotherapy, radiotherapy is discussed and hormone therapy has no place. Their prognosis is bleak and the evolution is marked by locoregional recurrences and distant metastases. We report two cases of metaplastic breast carcinoma diagnosed by histology supplemented by immunohistochemistry, the treatment consisted of a mastectomy with axillary dissection supplemented by chemotherapy.
Author Keywords: Tumor, breast, histopathology, immunohistochemistry, treatment, prognosis.
Volume 23, Issue 3, June 2018, Pages 285–289
Aida Abida1, Dalal Kacimi2, Mounia El Youssfi3, and Samir Bargach4
1 Service de gynécologie obstétrique cancérologie et grossesse à haut risque, Maternité Souissi, Université Mohamed V, Rabat, Morocco
2 Service de gynécologie obstétrique cancérologie et grossesse à haut risque, maternité Souissi, Université Mohamed V, Morocco
3 Service de gynécologie obstétrique cancérologie et grossesse à haut risque, maternité Souissi, Université Mohamed V, Rabat, Morocco
4 Department of Gynecology-Obstetrics-Oncology and High-Risk Pregnancy, Souissi Maternity Hospital, Ibn Sina University Hospital Center, Rabat, Morocco
Original language: French
Copyright © 2018 ISSR Journals. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Metaplastic breast carcinomas are rare tumors, represent less than 1% of invasive breast cancers, and constitute a heterogeneous group of tumors defined by the World Health Organization as infiltrating ductal carcinoma but with zones of metaplastic rearrangements of Epidermoid, fusiform, chondroid, bone or mixed type. Histopathology combined with immunohistochemistry makes it possible to make the diagnosis. Treatment combines surgery, and chemotherapy, radiotherapy is discussed and hormone therapy has no place. Their prognosis is bleak and the evolution is marked by locoregional recurrences and distant metastases. We report two cases of metaplastic breast carcinoma diagnosed by histology supplemented by immunohistochemistry, the treatment consisted of a mastectomy with axillary dissection supplemented by chemotherapy.
Author Keywords: Tumor, breast, histopathology, immunohistochemistry, treatment, prognosis.
Abstract: (french)
Les carcinomes métaplasiques du sein sont des tumeurs rares, représentent moins de 1% des cancers invasifs du sein, constituent un groupe hétérogène de tumeurs définis selon l’organisation mondiale de la santé comme étant un carcinome canalaire infiltrant mais comportant des zones de remaniements métaplasiques de type épidermoïde, à cellules fusiformes, chondroide, osseux ou mixte. L’histopathologie combinée à l’immunohistochimie permet de poser le diagnostic. Le traitement associe la chirurgie, et la chimiothérapie, la radiothérapie est discutée et l’hormonothérapie n’a pas de place. Leur pronostic est sombre et l’évolution est marquée par les récidives locorégionales et les métastases à distance. Nous rapportons 2 cas de carcinome métaplasique du sein dont le diagnostic a été pose par l’histologie complétée par l’immunohistochimie, le traitement a consisté en une mastectomie avec curage axillaire complété par chimiothérapie.
Author Keywords: Tumeur, sein, histopathologie, immunohistochimie, traitement, pronostic.
How to Cite this Article
Aida Abida, Dalal Kacimi, Mounia El Youssfi, and Samir Bargach, “Metaplastic breast carcinoma : About two cases,” International Journal of Innovation and Applied Studies, vol. 23, no. 3, pp. 285–289, June 2018.
