Volume 25, Issue 3, February 2019, Pages 1100–1106
Latifa Baddade1, Mohamed Berkani2, Mustapha Oubenali3, Abdelkader Ben Ali4, and Mohamed Mbarki5
1 University of Sultan Moulay Slimane, Faculty of Science and Technology, P.B 523, Beni Mellal, Morocco
2 University of Sultan Moulay Slimane, Faculty of Science and Technology, P.B 523, Beni Mellal, Morocco
3 Transdisciplinary Team of Analytical Science for Sustainable Development, University Sultan Moulay Slimane, Béni Mellal, Morocco
4 Université Mohammed V, Faculté des Sciences, Laboratoire de Chimie du Solide Appliquée, Rabat, Maroc
5 Department of chemistry and environment, Sultan Moulay Slimane University, Faculty of Science and Technology, Transdisciplinary Team of Analytical Science for Sustainable Development, PB 523, Beni Mellal, Morocco
Original language: French
Copyright © 2019 ISSR Journals. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
In Morocco, some so called ‘‘forgotten fruits’’ such as the ‘‘Zizyphus Lotus’’ fruits and the ‘‘Arbutus Unedo’’ fruits can be valorized in the context of regional sustainable development as local products. In addition, there is a rapidly increasing prevalence of the urolithiasis in the world. The Urolithiasis involves the formation of crystalline aggregates called "urinary stones" that are developed in the urinary tract, usually in the kidneys or ureters, but may also affect the bladder or urethra. The aim of this study is to evaluate the in vitro anti-lithiasic activity of selected ‘‘forgotten fruits’’. The anti-lithiasic activity was evaluated against the aggregation of calcium oxalate. ‘‘Zizyphus Lotus’’ - and ‘‘Arbutus Unedo’’ fruits samples were taken from six zones from Beni Mellal-Khenifra region. The seed of the two fruits species were subjected to a grinding mortar. The samples have been subsequently, submitted a cold maceration using distilled water during 48 hours. The study of the crystallization of calcium oxalate has been carried out by the polarizing optical microscope (PLM). Some aqueous extracts have an anti-crystallization effect on the aqueous solution of the studied lithogenous species.
Author Keywords: Urolithiasis, calcium oxalate, crystallization, PLM, valorization, Zizyphus Lotus, Arbutus Unedo, anti-lithiasic activity..
Latifa Baddade1, Mohamed Berkani2, Mustapha Oubenali3, Abdelkader Ben Ali4, and Mohamed Mbarki5
1 University of Sultan Moulay Slimane, Faculty of Science and Technology, P.B 523, Beni Mellal, Morocco
2 University of Sultan Moulay Slimane, Faculty of Science and Technology, P.B 523, Beni Mellal, Morocco
3 Transdisciplinary Team of Analytical Science for Sustainable Development, University Sultan Moulay Slimane, Béni Mellal, Morocco
4 Université Mohammed V, Faculté des Sciences, Laboratoire de Chimie du Solide Appliquée, Rabat, Maroc
5 Department of chemistry and environment, Sultan Moulay Slimane University, Faculty of Science and Technology, Transdisciplinary Team of Analytical Science for Sustainable Development, PB 523, Beni Mellal, Morocco
Original language: French
Copyright © 2019 ISSR Journals. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
In Morocco, some so called ‘‘forgotten fruits’’ such as the ‘‘Zizyphus Lotus’’ fruits and the ‘‘Arbutus Unedo’’ fruits can be valorized in the context of regional sustainable development as local products. In addition, there is a rapidly increasing prevalence of the urolithiasis in the world. The Urolithiasis involves the formation of crystalline aggregates called "urinary stones" that are developed in the urinary tract, usually in the kidneys or ureters, but may also affect the bladder or urethra. The aim of this study is to evaluate the in vitro anti-lithiasic activity of selected ‘‘forgotten fruits’’. The anti-lithiasic activity was evaluated against the aggregation of calcium oxalate. ‘‘Zizyphus Lotus’’ - and ‘‘Arbutus Unedo’’ fruits samples were taken from six zones from Beni Mellal-Khenifra region. The seed of the two fruits species were subjected to a grinding mortar. The samples have been subsequently, submitted a cold maceration using distilled water during 48 hours. The study of the crystallization of calcium oxalate has been carried out by the polarizing optical microscope (PLM). Some aqueous extracts have an anti-crystallization effect on the aqueous solution of the studied lithogenous species.
Author Keywords: Urolithiasis, calcium oxalate, crystallization, PLM, valorization, Zizyphus Lotus, Arbutus Unedo, anti-lithiasic activity..
Abstract: (french)
Au Maroc, des fruits dits oubliés comme dans les cas des fruits de jujubier (Zizyphus Lotus) et de l’Arbitus Unedo peuvent être valorisés dans le cadre du développement durable régional en tant que produits locaux. En outre, la prévalence d’urolithiase dans le monde augmente rapidement. L'urolithiase consiste à former des agrégats cristallins appelés « calculs urinaires » développés dans l'appareil urinaire, habituellement dans les reins ou les uretères, mais peuvent également affecter la vessie ou l'urètre. L’objectif du présent travail est d’évaluer l’effet anti-cristallisant, in vitro, des ‘‘fruits oubliés’’ de choix vis-à-vis de la formation de l'oxalate de calcium. Les échantillons de fruits de Z. Lotus et d’A. Unedo ont été prélevés dans six zones de la région de Béni Mellal-Khenifra. Les échantillons de l’amande de Z. Lotus et de fruit de l’A. Unedo ont été broyés à l’aide d’un mortier de façon à avoir une poudre fine pour l’amande de Z. Lotus et une purée pour le fruit de l’A. Unedo. En suite les échantillons ont été soumis à une macération à froid par l’utilisation de l’eau distillée pendant 48 heures. L'étude de la cristallisation, in vitro, de l'oxalate de calcium a été réalisée grâce au microscope optique à lumière polarisée (MOLP). Certains extraits aqueux présentent un effet anti- lithiasique sur la solution aqueuse de l’espèce lithogène étudiée.
Author Keywords: Urolithiase, oxalate de calcium, cristallisation, MOLP, valorisation, Zyziphus Lotus, Arbutus Unedo, activité anti-lithiasique.
How to Cite this Article
Latifa Baddade, Mohamed Berkani, Mustapha Oubenali, Abdelkader Ben Ali, and Mohamed Mbarki, “Activité anti-lithiasique des extraits aqueux des fruits de l’Arbutus Unedo et de l’amande de Zizyphus Lotus,” International Journal of Innovation and Applied Studies, vol. 25, no. 3, pp. 1100–1106, February 2019.
