[ Détermination de l’activité des enzymes hépatiques chez les consommateurs des bières, dans la ville de Gemena de 2022 - 2023, Province de Sud Ubangi, RDC ]
Volume 47, Issue 1, November 2025, Pages 127–137
Zachée Kombo Tebopele1, MAMBESA BAINAMBOKA Martin2, Daniel Mademogo3, Cherubin Sangi Kelamose4, Luc Boekoli Likonga5, Justin NGAWI6, and Richard Tanakula7
1 ISTM Gemena, Province du Sud Ubangi, RD Congo
2 Licencié en sciences infirmières/EASI, RD Congo
3 ISTM Gemena, Province du Sud Ubangi, RD Congo
4 ISTM Gemena, Province du Sud Ubangi, RD Congo
5 ISTM Gemena, Province du Sud Ubangi, RD Congo
6 Institut Supérieur des Techniques Médicales de Gemena, RD Congo
7 ISTM Gemena, Province du Sud Ubangi, RD Congo
Original language: French
Copyright © 2025 ISSR Journals. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
This study concerns the determination of hepatic enzyme activity in beer consumers. It was carried out in the city of Gemena, with the overall objective of determining hepatic enzyme activity in beer consumers, evaluating the liver function of beer consumers, and detecting possible hepatic dysfunctions. The study involved a total of 60 confirmed beer-consuming subjects recruited mainly from students of ISTM Gemena in a purposive sampling because the characteristics of the respondents were well known and determined in advance to participate in the study. Laboratory analysis of ALT (GPT/ALAT), AST (GOT/ASAT) and GGT performed on whole blood collected in plain tubes and centrifuged to obtain serum revealed abnormally elevated enzymatic activity with estimated values approximating: 40.39±3.2 U/l, 55.44±9 U/l and 48.11±5.8 U/l respectively for GPT, GOT and GGT compared with 37.9±3.3 U/l, 35.36±3.2 and 40.96±3.3. It should be noted that there were more male consumers than female consumers (73.3% versus 16 female cases, i.e. 26.7%). The mean age of the respondents was between 20 and 30 years. The beer most consumed by the respondents was Castel (a beer imported from West Africa).
Author Keywords: determination, activity, enzymes, hepatic, consumers, beer.
Volume 47, Issue 1, November 2025, Pages 127–137
Zachée Kombo Tebopele1, MAMBESA BAINAMBOKA Martin2, Daniel Mademogo3, Cherubin Sangi Kelamose4, Luc Boekoli Likonga5, Justin NGAWI6, and Richard Tanakula7
1 ISTM Gemena, Province du Sud Ubangi, RD Congo
2 Licencié en sciences infirmières/EASI, RD Congo
3 ISTM Gemena, Province du Sud Ubangi, RD Congo
4 ISTM Gemena, Province du Sud Ubangi, RD Congo
5 ISTM Gemena, Province du Sud Ubangi, RD Congo
6 Institut Supérieur des Techniques Médicales de Gemena, RD Congo
7 ISTM Gemena, Province du Sud Ubangi, RD Congo
Original language: French
Copyright © 2025 ISSR Journals. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
This study concerns the determination of hepatic enzyme activity in beer consumers. It was carried out in the city of Gemena, with the overall objective of determining hepatic enzyme activity in beer consumers, evaluating the liver function of beer consumers, and detecting possible hepatic dysfunctions. The study involved a total of 60 confirmed beer-consuming subjects recruited mainly from students of ISTM Gemena in a purposive sampling because the characteristics of the respondents were well known and determined in advance to participate in the study. Laboratory analysis of ALT (GPT/ALAT), AST (GOT/ASAT) and GGT performed on whole blood collected in plain tubes and centrifuged to obtain serum revealed abnormally elevated enzymatic activity with estimated values approximating: 40.39±3.2 U/l, 55.44±9 U/l and 48.11±5.8 U/l respectively for GPT, GOT and GGT compared with 37.9±3.3 U/l, 35.36±3.2 and 40.96±3.3. It should be noted that there were more male consumers than female consumers (73.3% versus 16 female cases, i.e. 26.7%). The mean age of the respondents was between 20 and 30 years. The beer most consumed by the respondents was Castel (a beer imported from West Africa).
Author Keywords: determination, activity, enzymes, hepatic, consumers, beer.
Abstract: (french)
La présente étude porte sur la détermination de l’activité des enzymes hépatiques chez les consommateurs des bières. Elle a été réalisée dans la ville de Gemena, avec comme objectif global de déterminer l’activité des enzymes hépatique chez les consommateurs des bières envie évaluer la fonction hépatique des consommateurs des bières et de déceler d’éventuels dysfonctionnements hépatiques. L’étude a porté sur un total de 60 sujets consommateurs avérés de la bière recrutés essentiellement parmi les étudiants de l’ISTM Gemena dans un échantillonnage raisonné car les caractéristiques des enquêtés ont été bien connues et déterminées à l’avance pour être participant à l’étude. Une analyse au laboratoire de GPT/ALAT, GOT/ASAT et GGT à partir du sang total prélevé dans des tubes secs, centrifugé pour obtenir le sérum a permis de déceler une activité enzymatique anormalement élevée avec une estimation envoisinant: 40,39±3,2 U/l, de 55,44±9 U/l et de 48,11±5,8 U/l respectivement pour GPT, GOT et GGT contre 37,9±3,3U/l, 35,36±3,2 et 40,96±3,3. Il faut noter qu’il y a eu plus des consommateurs masculins que les consommateurs féminins (73,3% contre 16 cas de celles de sexe féminin, soit 26,7%). L’âge moyen des enquêtés se situant entre 20 et 30 ans. La bière la plus consommée par les enquêtés étant le Castel (une bière importée de l’Afrique de l’Ouest).
Author Keywords: détermination, activités, enzymes, hépatiques, consommateurs, bière.
How to Cite this Article
Zachée Kombo Tebopele, MAMBESA BAINAMBOKA Martin, Daniel Mademogo, Cherubin Sangi Kelamose, Luc Boekoli Likonga, Justin NGAWI, and Richard Tanakula, “Determination of liver enzyme activity among beer consumers in the city of Gemena from 2022 - 2023, Sud Ubangi Province, DRC,” International Journal of Innovation and Applied Studies, vol. 47, no. 1, pp. 127–137, November 2025.
