The present study was carried out in Karakoro commune to assess the effects of incorporating powder from Moringa oleifera leaves on growth performance, laying and egg quality of ISA Brown laying hens. To do this, three batches of 100 laying hens were made and fed with three diets containing different levels of incorporation of Moringa oleifera powder. The experiment lasted eight weeks. Lot A was fed with feed without incorporation of Moringa oleifera. Lots B and C were fed feed containing Moringa oleifera leaf powder incorporation rates of 1% and 5%, respectively. In terms of the growth performance of the laying hens, the results showed that the average weight of the subjects of batch A which was 1.64 g at the 29th week was higher than those of batches B and C with respective weights of 1, 61 g and 1.57 g without significant difference (P(0.05). On the other hand, in terms of spawning performance, batch C obtained better results. The average egg weight of the laying hens in batch C (58.6 g) was greater than that of batch B (50.19 g) and batch A (47.85 g). Ultimately, breeders should incorporate Moringa oleifera powder into the diets of laying hens to improve laying performance.