To assess the influence of Jatropha curcas cultivation on maize yield in a cropping association, a study was conducted on the application farm of the Ecole Régionale d'Agriculture du Sud in Bingerville from 2015 to 2016. The study aimed to determine the appropriate Jatropha planting density to improve maize yield in a cropping association. The experiment consisted in setting up a randomized complete block design with three replications, including three treatments T1 (2*2m); T2 (3*2m) and T3 (4*2m) based on the spacing of Jatropha curcas plants compared to a control T0 (control without jatropha). Morphological and yield parameters of Jatropha curcas and maize were assessed respectively. The results obtained show that the Jatropha-maize association had no significant effect (P > 0.05) on the agro-morphological parameters (growth, development and yield) of Jatropha curcas regardless of the treatment. On the other hand, a significant effect (P < 0.05) of the Jatropha-maize association was observed on plant biomass and maize yield, particularly with treatment T2. In conclusion, this experiment demonstrates that it is possible to harmoniously integrate regular row spacing (intercropping) in Jatropha curcas plantations during the juvenile period of the trees provided that the main crop (Jatropha curcas) is at a spacing of 3*2 m.