Objectives: It consisted in evaluating psychosocial risk factors among midwives/ maieuticians of Yalgado Ouédrago University Hospital Center of Ouagadougou. Methodology: This was a descriptive, cross-sectional and analytical study, carried out using an anonymous self-questionnaire. The Karasek scale was used to identify risk situations. Data were entered and analyzed using Epi info version 7.0 software. The significance level chosen was p < 5% to assess the link between socio-professional variables and stress. Result: A total of 42 midwives/maieuticians were participated in the study. The average age was 38 years old. Women predominated (71.4%). The average weekly working hours was 45 hours. The average number of monthly guards was 6. The average seniority in the profession was 10.5 years. The prevalence of psychosocial risks was 88.1% for psychological demand, 57.1% for low decision latitude and 64.3% for low social support. Value conflicts (71.4%), job and work insecurity (52.4%) and emotional demands (21.4%) were collected. The prevalence of job train was 52.4% and that of isostrain was 26.2%. The correlation between socio-professional variables and stress was not statistically significant (p˃0.05). Conclusion: Psychosocial risks are omnipresent among midwives/maieuticians. It is urgent to promote the creation of occupational health services in care settings in order to improve the psychosocial environment and to detect the suffering of caregivers early.