In Ivory Coast, the rational management of waste from forestry operations (also known as related waste) is one of the State’s environmental priorities. It must meet the challenges of the circular economy by proposing various ways of recovery, including the recovery of bioactive molecules from species. Thus, this study aims to evaluate the bioactive potential (antioxidant and antifungal activity) of extracts of three sustainable species from Côte d’Ivoire: Milicia excelsa (Iroko), Mansonia altissima (Bete), Nauclea diderrichii (Badi). The antioxidant activity was determined by ABTS tests and the antifungal activity was evaluated against a brown rot, Coniophorora puteana in in vitro condition. The Bete extract showed the highest antifungal activity: the concentration 6 mg/mL led to a total inhibition of the mycelium growth, against 8 mL/mg for Iroko and Badi. Regarding antioxidant activity, Badi extract (66.898%) showed the highest percentage of inhibition, followed by Iroko (55,25%) and Bété (52,12%).