The emergence of obesity and diabetes in Ivory Coast due to changes in the population’s lifestyle led us to conduct this study. Ivorian flora abounds in many plants with pharmacological properties. Through this study, we want to find the plants that were best suited to treat both obesity and diabetes. We have found eighteen (18) plant species used for the treatment of diabetes and ten (10) for the treatment of obesity. Among these plants, two of them were the most indicated for the treatment of diabetes, it is Picralima nitida and Catharantus roseus. Similarly for obesity is Cassia senna which was most appropriate. However, it is Moringa oleifera and Phyllanthus amarus that have been mentioned for the treatment of both obesity and diabetes. The Moringa oleifera is used as a dietary supplement. Our study shows that the Moringa oleifera can be recommended for the treatment of diabetes and obesity.