Volume 10, Issue 2, February 2015, Pages 687–693
Souad Rabi1, Malika Echajia2, Constant TCHEKA3, Najat Elhadiri4, and Mohamed Mbarki5
1 Department of chemistry and environment, Sultan Moulay Slimane University, Faculty of Science and Technology, Transdisciplinary Team of Analytical Science for Sustainable Development, PB 523, Béni Mellal, Morocco
2 Department of chemistry and environment, Sultan Moulay Slimane University, Faculty of Science and Technology, Transdisciplinary Team of Analytical Science for Sustainable Development, PB 523, Béni Mellal, Morocco
3 Laboratory of Physical and Theoretical Chemistry, Department of Inorganic Chemistry, Faculty of Science, P.O. Box 812, Yaoundé, Cameroon
4 Department of chemistry, Cadi Ayyad University, Faculty of Science Semlalia, Laboratory of reactivity of materials and process optimization, PB 2390, Marrakech, Morocco
5 Department of chemistry and environment, Sultan Moulay Slimane University, Faculty of Science and Technology, Transdisciplinary Team of Analytical Science for Sustainable Development, PB 523, Beni Mellal, Morocco
Original language: English
Copyright © 2015 ISSR Journals. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
The present work reports a comparative study of spontaneous crystalluria for non- and goitrous patients with the aim to determine its correlation with parathyroid gland activity and goiter etiology. The crystalluria was accessed based on optical polarized light microscopy (OPLM). Goiter presents high woman predominance with an average age of 35.6 years. The frequency of majority constituents in crystalluria is age dependent and amorphous complex carbonated phosphates (ACCP) and uric acid (UA) are the frequent chemical species. The observed hyperphosphaturia can be explained by the estrogen's activity on parathyroid cells proliferation. The presence of oxalo-calcic crystalluria confirms hyperparathyroidism as one of the hypercalciuric kidney stone etiology. Clinical goiter diagnostic and treatment could be followed and confirmed by a simple fluctuations follow-up of crystalluria composition according to phosphate and calcium species.
Author Keywords: Crystalluria, hyperphosphaturia, hypercalciuria, goiter etiology, hyperparathyroidism, kidney stone, OPLM.
Souad Rabi1, Malika Echajia2, Constant TCHEKA3, Najat Elhadiri4, and Mohamed Mbarki5
1 Department of chemistry and environment, Sultan Moulay Slimane University, Faculty of Science and Technology, Transdisciplinary Team of Analytical Science for Sustainable Development, PB 523, Béni Mellal, Morocco
2 Department of chemistry and environment, Sultan Moulay Slimane University, Faculty of Science and Technology, Transdisciplinary Team of Analytical Science for Sustainable Development, PB 523, Béni Mellal, Morocco
3 Laboratory of Physical and Theoretical Chemistry, Department of Inorganic Chemistry, Faculty of Science, P.O. Box 812, Yaoundé, Cameroon
4 Department of chemistry, Cadi Ayyad University, Faculty of Science Semlalia, Laboratory of reactivity of materials and process optimization, PB 2390, Marrakech, Morocco
5 Department of chemistry and environment, Sultan Moulay Slimane University, Faculty of Science and Technology, Transdisciplinary Team of Analytical Science for Sustainable Development, PB 523, Beni Mellal, Morocco
Original language: English
Copyright © 2015 ISSR Journals. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
The present work reports a comparative study of spontaneous crystalluria for non- and goitrous patients with the aim to determine its correlation with parathyroid gland activity and goiter etiology. The crystalluria was accessed based on optical polarized light microscopy (OPLM). Goiter presents high woman predominance with an average age of 35.6 years. The frequency of majority constituents in crystalluria is age dependent and amorphous complex carbonated phosphates (ACCP) and uric acid (UA) are the frequent chemical species. The observed hyperphosphaturia can be explained by the estrogen's activity on parathyroid cells proliferation. The presence of oxalo-calcic crystalluria confirms hyperparathyroidism as one of the hypercalciuric kidney stone etiology. Clinical goiter diagnostic and treatment could be followed and confirmed by a simple fluctuations follow-up of crystalluria composition according to phosphate and calcium species.
Author Keywords: Crystalluria, hyperphosphaturia, hypercalciuria, goiter etiology, hyperparathyroidism, kidney stone, OPLM.
How to Cite this Article
Souad Rabi, Malika Echajia, Constant TCHEKA, Najat Elhadiri, and Mohamed Mbarki, “Study of crystalluria in goitrous patients,” International Journal of Innovation and Applied Studies, vol. 10, no. 2, pp. 687–693, February 2015.
