Bisalbuminemia is a rare electrophoretic abnormality of the albumin fraction, characterized by a doubling of this fraction on the electrophoretic trace of serum proteins, reflecting the presence in the same individual of normal plasma albumin and structurally altered albumin, which may be of acquired etiology, rarely hereditary. The aim of this article is to study the etiologies and prevalence of bisalbuminemias associated with nephropathies discovered on serum protein electrophoresis at the biochemistry laboratory of the university hospital Ibn Rochd in Casablanca. This is a retrospective study of serum protein electrophoretic capillary tracings revealing bisalbuminemia in patients hospitalized in the nephrology department at university hospital Ibn Rochd in Casablanca over an 18-month period. 29 electrophoretic profiles out of 242 showed bisalbuminemia, i.e. 12% of all electrophoretic tracings in 29 patients presenting with acute or chronic nephropathy. The average age was 45±22 years, with a sex ratio (M/F) of 2.22. The etiologies of the nephropathies were dominated by renal amyloidosis with 24.14%, followed by minimal glomerular lesion nephropathies, extramembranous glomerulonephritis and lupus nephropathies with 17.24% each, and finally membranoproliferative glomerulonephritis with 6.9%. Among secondary etiologies, betalactam use was highlighted in 13.8% of cases, no patient in the series had a labelled pancreatopathy, and the presence of a monoclonal gammapathy was objectified in only one case in the series. This study illustrates the varied etiologies of bisalbuminemia associated with nephropathy, requiring detailed knowledge to enable proper interpretation of electrophoretic profiles.