The effect of soil salinity on some agrophysiological parameters at different stages of growth (Elongation and Heading) was studied in four varieties of durum wheat (Triticum durum Desf.) Namely: Carioca (V1), Karim (V2) Tarik (V3) and Tomouh (V4), under control of three saline levels (3, 6 and 9 g / l NaCl). The results obtained show that the salinity leads to an increase in the water content, the sugar content and the Na+ and Cl- content. However, a decrease in plant length, number of leaves, number of plants, last leaf length, fresh and dry biomass, K+ content, K+ / Na+ ratio, and number of spikes was observed. The results prove the tolerance to salinity of the variety Carioca (V1) compared to other varieties. This tolerance is manifested by a lower decrease in fresh and dry biomass, K+ content and yield. Also, this variety was characterized by a lower salt sensitivity index (I.S.R.S) and a low accumulation of Na+ and Cl- especially at higher concentrations (6 and 9 g / l NaCl).