Palm wine, known as atan in Benin, is a sweet beverage extracted from the oil palm (Elaeis guineens). Highly prized by the population for its high nutritional value, its marketing is very limited due to a lack of or inappropriate means of preservation. In the search for palliatives, the present study aims at the Bio-preservation of palm wine by using orange peels to extend its shelf life. To achieve this objective, the preservative effect of orange peels was evaluated, and the stabilized wine was characterized in physicochemical, nutritional, microbiological and organoleptic terms. Palm wine samples graded A, B and C received 10g, 15g and 20g of orange peel respectively. During the storage period, the bottles that received the peelings in this order burst after one, two, three and four weeks respectively. The flasks that burst early were those with a low peel incorporation rate. The 33cL bottles containing palm wine and 25g orange peel resisted bursting up to 4 weeks of storage. Analysis of physicochemical and nutritional parameters showed that stabilized palm wine was richer in potassium, magnesium, sodium and calcium than the unstabilized control wine. Microbiological analysis of the stabilized palm wine showed that the yeast, Escherichia coli and Staphylococcus loads were lower than in the unstabilized wine. In terms of sensory quality, the study showed that consumers rated the consistency, color and taste of stabilized wines higher than those of unstabilized (control) wines.