Soil erosion is a natural process with worrying environmental and socio-economic consequences in watersheds. A quantitative and spatiotemporal assessment of this phenomenon is imperative and must be taken into account for integrated management of the Sassandra catchment. LANDSAT Satellite images, rainfall data, the digital elevation model, soil data, Geographic Information System (GIS) software and the Revised Universal Soil Loss Equation (RUSLE) were used to assess annual soil losses in the Sassandra catchment for the years 1986, 2002 and 2022. The results of the study show that soil erosion is increasing in the Sassandra catchment. The average soil losses obtained are 27, 37 and 39 million t/ha/yr respectively for the years 1986, 2002 and 2022.