Wegener granulomatosis is an autoimmune small vessel vasculitis highly associated with anti-neutrophil cytoplasmic antibodies and characterized by necrotizing granuloma of respiratory tract, disseminated vasculitis and glomerulonephritis. Its clinical manifestations and organ involvement arevery widely.
The etiology of Wegener granulomatosis is linked to environmental and infectious triggers inciting onset of disease in genetically predisposed individuals. Complications most often occur when the disease is not treated. Kidney disease causes glomerulonephritis with hematuria. It can quickly get worse with kidney failure, but can be prevented when the condition are controlled by medicines.
We report a case of a pregnant woman with Wegener
Ovaries are a frequent site of metastasis of the breast cancer. The annexielles metastases of breast cancer often present as a challenge for diagnosis and therapeutic.. Distinction between ovarian metastasis and primary ovarian cancer may sometimes be difficult. The surgical resection tends to increase survival a surgical option should consist of at least bilateral oophorectomy, even when the contralateral ovary appears to be normal. We presente cas of patient of 36years old female, followed by breast cancer since 2011 stade 1 initially (T1N1Mx), was underwent Patey (infiltrating ductal carcinoma) followed radiotherapy and chemotherapy, hormonotherapy, four years later the patient complaint of abdominal distention, abdominal ultrasound showed ovarian masse then open laparoscopy was done, left adnexectomy was realized and finally histological diagnosis revealed Ovarian metastasis of the breast cancer.
The obesity, factor of morbimortalite, is considered as a real health public problem. In gynecology, its consequences on the fertility and the contraception are sever and the obesity is at the origin of important obstetric complications that must make consider these pregnancies as at risk. Our practices have to take into account these complications by assuring an adapted and premature care to improve the maternal and neonatal outcomes.
Feto-maternal red cell alloimmunization is defined by the presence in a pregnant woman of alloantibodies directed against blood group antigens present on the red blood cells of the fetus and inherited by the father. It arises from the immune response to a first contact to these same antigens during a prior transfusion, transplant or pregnancy. The placental transfer and the fixation of the antibodies on the fetal red cells antigenic targets lead to a haemolysis in the fetus and the newborn. The resulting haemolytic disease can show different clinical forms, from a mild anaemia with neonatal hyperbilirubinemia to a major fetal damage with stillbirth caused by hydrops fetalis. The objective of management strategies of feto-maternal alloimmunization is to detect and monitor maternal alloimmunization and to appreciate the effects on the fetus or the newborn.
Endometrial stromal tumors are rare and are less than 5% of uterine tumors. They are composed of cells closely resembling endometrial stromal cells in the proliferative phase. They are classified into two categories: the stromal nodules, benign, and endometrial stromal sarcomas, including endometrial stromal sarcoma (low grade) and undifferentiated endometrial sarcoma (formerly high grade). The diagnosis is most often does retrospectively after histological analysis of the surgical specimen. The classical treatment is abdominal hysterectomy with bilateral oophorectomy. The adjuvant treatment are not yet established and the optimal treatment of this entity is still not clear. We report the case of a patient of 46 years, admitted for pelvic pain with abdomino-pelvic mass Ultrasound and MRI have found a polymyomatous uterus with interstitial body mass with a compression effect on the endometrium. The patient underwent total hysterectomy with bilateral oophorectomy, Histology with additional immunohistochemical concluded endometrial stromal sarcoma of low grade, stage IB, hormone receptor-negative. Through this rare case and with a literature review, we focus on the epidemiological, diagnostic, therapeutic and prognostic of that entity.
The Uterine fibroma pathology is common and the relationships between fibroids and pregnancy are triple: Fibroids can prevent conception and implantation; the fibroid may complicate the course of pregnancy, at delivery and postpartum period 'and pregnancy-induced condition can facilitate the development of fibroids to complications. We report the case of a patient who was followed in our department from 17 weeks+2days of pregnancy whose ultrasound revealed fibroid located in the uterine isthmus .Through our case and with the support of the literature, We will insist the complications that can occur and understand the importance of diagnosis and early management of this entity.
The malignant germinal tumors of the ovary are rare, but a rest curable whatever is the stage. We report the observation of 24 years old patient, married, never get pregnant , who was sent in our hospital for pelvic pains, the gynecological examination revealed an abdominal mass in the umbilical level . The pelvic ultrasound and the abdominal CT scan showed a heterogeneous solid mass in depends on the ovary. A laparotomy was indicated, allowed a right adnexectomy. The anatomopathologique examination is returned in favor of a dysgerminoma. The germinal tumors of the ovary are rare tumors which affect the girls and the young women, they have a good prognosis whether his stage with an optimal treatment and the majority of the patients keep their reproduction functions.