Medicinal plants can be an important element in the treatment of metabolic and cardiovascular diseases involved in the development of metabolic syndrome (MetS). The objective of this work was to evaluate the knowledge of medicinal plants with antidiabetic, antihypertensive and slimming properties used by the populations of the N’Zi Region. Ethnobotanical surveys were conducted in this region with 554 households and 17 healers using a questionnaire. This study made it possible to inventory a total of 69 medicinal plants used against the components of MetS. With 33 species used in households and 56 species used by healers. Spondias mombin (FC= 5.68%), Bambusa vulgaris (FC= 4.55%) and Citrus limon (FC= 4.55%) are the best known among healers. Among the households visited, Persea americana (FC= 23.50%) and Phyllanthus amarus (FC=9,29%) was the best known. The results obtained in this study show that Ananas comosus, Citrus limon and Parkia biglobosa are used both in healers and in households to treat hypertension, type 2 diabetes and obesity. These results show that these plants could be used as improved traditional medicines and could be used in the treatment of certain components of MetS such as diabetes, hypertension and obesity.
The bacteria producing beta-lactamases extended spectrum are the leading cause of treatment failure observed in the treatment of bacterial infections. This study aims to evaluate the antibacterial effects of extracts hexanical, 70% methanol and aqueous leaf Spondias mombin (Desr.) A. Juss. (Anacadiaceae) on six clinical isolates of Enterobacteriaceae producing beta-lactamases with extended spectrum (ESBL) and a reference strain. The study of the antibacterial activity of the extracts was performed by the medium diffusion method and agar dilution Mueller-Hinton. For phytochemical screening extracts, chromatographic characterization method thin layer was used. It emerged from this study that the aqueous and hydro-alcoholic extracts are actives. They are bactericidal for the majority of tested strains with MICs ranging from 0.39 to 1.56 mg / mg for the 70% methanol extract and 0,39 to 3.125 mg / ml for the aqueous extract. The phytochemical screening revealed a wealth of secondary metabolites such as saponins, tannins, flavonoids, sesquiterpenes, polyphenols, coumarins may be beneficial in the treatment of many diseases in Enterobacteriaceae.